On April 18, 2018, CBS renewed for a fifth season (along with related series are NCIS, NCIS: LA and Hawaii Five-0).
On May 17, 2018, it reveals that Brad Kern is stepping down from the series after complaints about his behavior in the writers' room and on the set of the series which ranged from being verbally abusive to staffers and making sexually charged comments about his personal relationships and sex life in the writer's room to a complaint of Kern's habit of bringing women he dated to the set and sometimes giving them bit parts in the series. Franklin has not been accused of directly sexually harassing or engaging in physical misconduct with any staffers. The following day, Christopher Silber announced as the new executive producer and showrunner for the fifth season replacing Kern.
As the team searches for a former IRA bomb-maker who was smuggled into the city, they are joined by Special Agent Hannah Khoury is Sonja Percy's replacement and Pride's temporary replacement for his medical leave.
While NCIS investigates the murder of a Navy intelligence officer killed during a conference for foreign diplomats, the key witness cozies up to Sebastian. Also, Pride has some trouble adjusting to his new position at the agency.
After a petty officer is found murdered under a shrimping boat, the NCIS investigation uncovers a conspiracy in the tight-knit local fishing community. Also, Lasalle awaits the final results of the tax fraud investigation into his family’s company.